| Identifier | HPI027241 |
| Interaction | GADD45 beta <==> p53 |
| Role & State | --- |
| Interaction Type | IT:0000259,protect; IT:0000242,direct; IT:0000078,regulation; IT:0000099,formation; IT:0000132,methylation; |
| Biological Process | --- |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 15509538_15, These findings suggested that methylation might play a crucial role in the epigenetic regulation of GADD45beta in hepatocyte transformation that may be directed by p53 status.
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| Reference | 17591973_8, Thus, our results suggest that GADD45beta induction by SAMe via NF-kappaB may represent a novel mechanism of SAMe-mediated hepatoprotection, with p53 playing an important role.
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