| Identifier | HPI103521 |
| Interaction | p53 <==> NS5A |
| Role & State | --- |
| Interaction Type | IT:0000076,inhibition; IT:0000030,abrogate; IT:0000227,bind; IT:0000275,mediate; |
| Biological Process | BP:0006915,apoptosis; BP:0006916,anti-apoptosis; |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 12101418_9, The p53-induced apoptosis was abrogated by NS5A and the inhibition effect correlates well with the binding ability of NS5A to p53.
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| Reference | 12379483_6, Mutants of TBP and p53 showed reduced binding to NS5A.
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| Reference | 12925958_4, We then chose the p53-negative Hep3B HCC cell to investigate the mechanism of anti-apoptosis mediated by NS5A.
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