| Identifier | MPI47652 |
| Interaction | p53 <==> SSAT |
| Role & State | RS:0000077,regulator; |
| Interaction Type | IT:0000122,upregulation; IT:0000114,activation; IT:0000078,regulation; |
| Biological Process | BP:0007049,cell cycle; BP:0040007,growth; BP:0016049,cell growth; |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 15888550_10, The distinct and sequential upregulation of SSAT, p21, and stathmin, along with biochemical activation of the polyamine catabolic pathway in IRI in vivo and the demonstration of p53-p21 upregulation by SSAT and putrescine in vitro, points to the important role of regulators of cell growth and cell cycle progression in the pathophysiology and/or recovery in liver IRI.
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