| Identifier | MPI48172 |
| Interaction | phospho-JNK <==> p53 |
| Role & State | RS:0000002,activity; |
| Interaction Type | IT:0000128,phosphorylation; IT:0000148,catalyse; |
| Biological Process | BP:0070265,necrosis; |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 12492400_9, In conclusion, phospho-JNK may catalyse phosphorylation of p53 on Ser-15 in Se-deficient mouse liver under moderate oxidative stress, and attenuation of that cascade by low levels of GPX1 activity is associated with its protection against the pro-oxidant-induced liver aponecrosis. |