Detail information of PPI "HPI005646"

InteractionAhR  <==>  p53
Role & State        ---
Interaction TypeIT:0000128,phosphorylation; IT:0000168,inhibit; IT:0000078,regulation; IT:0000364,acetylation;
Biological Process        ---
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference20299546_9, These results suggest that AhR ligands such as TCDD might contribute to tumor progression by inhibiting p53 regulation (phosphorylation and acetylation) triggered by genotoxicants via the increased expression of the metastasis marker AGR2.