Detail information of PPI "HPI007946"

InteractionAurora-A  <==>  p53
Role & State        ---
Interaction TypeIT:0000271,express;
Biological ProcessBP:0008219,cell death; BP:0031099,regeneration; BP:0070265,necrosis;
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference19435814_0, Aurora-A overexpression in mouse liver causes p53-dependent premitotic arrest during liver regeneration.
Reference19435814_7, Indeed, the premitotic arrest and abnormal cell death, mainly necrosis, caused by Aurora-A overexpression were genetically rescued by p53 knockout.