Detail information of PPI "HPI009101"

InteractionBax  <==>  p53
Role & State        ---
Interaction TypeIT:0000259,protect; IT:0000271,express;
Biological ProcessBP:0006915,apoptosis;
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference12925958_12, These results suggest that HCV NS5A as a Bcl-2 homologue interacts with Bax to protect p53-negative HCC cells from NaPB-induced apoptosis.
Reference17191126_5, Bax expression was up-regulated following high levels of p53 expression, while bcl-2 expression was not altered by the level of p53 expression.