Detail information of PPI "HPI009294"

InteractionBcl2  <==>  P53
Role & StateRS:0000071,cluster; RS:0000080,suppressor;
Interaction TypeIT:0000176,suppress;
Biological Process        ---
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference21656028_4, First, adenovirus-mediated Hhex delivery into the hepatoma cell line, Hepa1-6, resulted in decreased expression of several proto-oncogenes (c-Jun and Bcl2), increased expression of some tumor suppressor genes (P53 and Rb), and enhanced expression of a cluster of hepatocytic and bile ductular markers.