Detail information of PPI "HPI071353"

InteractionTAp73 alpha and -beta proteins  <==>  p53
Role & StateRS:0000078,repressor;
Interaction TypeIT:0000174,repress;
Biological ProcessBP:0006915,apoptosis; BP:0007050,cell cycle arrest; BP:0007049,cell cycle;
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference19509292_2, Although TAp73alpha and -beta proteins are capable of inducing cell cycle arrest, apoptosis, and differentiation, DeltaNp73 acts in many cell types as a dominant-negative repressor of p53 and TAp73.