Detail information of PPI "HPI074048"

InteractionTRAIL  <==>  p53
Role & State        ---
Interaction TypeIT:0000080,effect;
Biological ProcessBP:0008219,cell death;
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference21725212_7, While the synergistic effect of quinacrine with TRAIL appears to be in part independent of p53, knockdown of p53 in HepG2 cells by siRNA results in more cell death after treatment by quinacrine and TRAIL.