Detail information of PPI "HPI074568"

InteractionTaiwanin A  <==>  p53
Role & State        ---
Interaction TypeIT:0000114,activation; IT:0000252,arrest;
Biological ProcessBP:0006915,apoptosis; BP:0007049,cell cycle;
Biological Function        ---
Subcelluar LocationSCL:0000023,microtubule;
Detection Method        ---
Reference17182066_7, Our results demonstrate that Taiwanin A can act as a new class of microtubule damaging agent, arresting cell cycle progression at mitotic phase and inducing apoptosis through the activation of p53.