Detail information of PPI "HPI087941"

Interactioncyclin D1 and estrogen receptor (ER) alpha  <==>  p53
Role & StateRS:0000067,receptor;
Interaction TypeIT:0000032,increase;
Biological Process        ---
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference19168586_3, LXR suppressed messenger RNA and/or protein expression of Skp2, cyclin A2, cyclin D1 and estrogen receptor (ER) alpha, whereas it increased the expression of p53 at the protein level and maintained the retinoblastoma protein in a hypophosphorylated active form.