| Identifier | HPI103436 |
| Interaction | p53 <==> E6/E7 |
| Role & State | --- |
| Interaction Type | IT:0000114,activation; |
| Biological Process | --- |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 19177844_3, In addition to telomerase activation by the introduction of human telomerase reverse transcriptase (hTERT), inactivation of the p16/RB pathway and/ or p53 by E6/E7 of human papillomavirus type 16 (HPV16) has been shown to be useful for efficient immortalization of several human cell types. |