Detail information of PPI "HPI103489"

Interactionp53  <==>  IL-6
Role & StateRS:0000067,receptor;
Interaction Type        ---
Biological ProcessBP:0032635,IL-6 production;
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference15555057_7, We investigated the role of human IL-6 on p53 null immortalized murine oval cell lines (PIL), finding that they express transcripts for the IL-6 receptor and gp 130, STAT-3 is phosphorylated upon IL-6 stimulation, IL-6 induces IL-6 production, and proliferation is induced by IL-6.