Detail information of PPI "HPI103491"

Interactionp53  <==>  IR promoter
Role & State        ---
Interaction TypeIT:0000271,express;
Biological ProcessBP:0010467,gene expression;
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference8665514_7, To examine possible mechanisms by which p53 may regulate IR gene expression, we show that p53 can repress the IR promoter and that a dominant-negative p53 (248Q) can de-repress the promoter in cells containing normal p53.