Detail information of PPI "HPI020699"

IdentifierHPI020699
InteractionDLC1  <==>  p53
Role & StateRS:0000077,regulator; RS:0000080,suppressor;
Interaction TypeIT:0000176,suppress;
Biological ProcessBP:0032502,development;
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference18593873_2, A recent study in Genes Development by Xue and colleagues (1439-1444) now provides in vivo evidence that DLC1, a negative regulator of Rho, is a tumor suppressor gene deleted almost as frequently as p53 in common cancers such as breast, colon, and lung.