Detail information of PPI "HPI022829"

IdentifierHPI022829
InteractionEGF-R  <==>  p53
Role & StateRS:0000002,activity;
Interaction TypeIT:0000271,express;
Biological Process        ---
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference11261824_3, EGF-R expression was related to lymph node metastasis, aberrant p53 expression, proliferating activity, and carcinoma differentiation. c-erbB-2 expression was observed in more than 50% of the cases, but was not related to any clinicopathological features, c-erbB-3 expression was linked to lymph node metastasis, and c-erbB-4 expression was directly related to proliferating activity and lymph node metastasis.