| Identifier | HPI023343 |
| Interaction | ERCC1 <==> p53 |
| Role & State | --- |
| Interaction Type | IT:0000252,arrest; IT:0000152,accelerate; |
| Biological Process | BP:0006260,DNA replication; BP:0006260,replication; |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 10834928_0, Nucleotide excision repair gene (ERCC1) deficiency causes G(2) arrest in hepatocytes and a reduction in liver binucleation: the role of p53 and p21.
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| Reference | 10834928_8, The most dramatic feature of the ERCC1-deficient liver phenotype, the accelerated polyploidy, is not rescued by p53 deficiency, but we show that p53 is responsible for the reduced DNA replication and binucleation.
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