| Identifier | HPI025737 |
| Interaction | FTY720 <==> p53 |
| Role & State | --- |
| Interaction Type | IT:0000128,phosphorylation; IT:0000275,mediate; IT:0000139,dephosphorylation; |
| Biological Process | BP:0006915,apoptosis; |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 15297371_10, In conclusion, FTY720 is a novel anticancer agent that induces apoptosis of hepatoma cell lines both in vitro and in vivo through PI3-K-mediated Akt dephosphorylation in a p53-independent manner. |