Identifier | MPI24513 |
Interaction | P53 <==> TGF-beta |
Role & State | --- |
Interaction Type | IT:0000068,transcription; IT:0000114,activation; IT:0000078,regulation; |
Biological Process | --- |
Biological Function | --- |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 18813803_12, GLI2 expression is regulated based on the balance of P53, Notch, and TGF-beta signaling, and Hedgehog signaling activation results in cell survival and proliferation due to transcriptional activation of Hedgehog-target genes, and also partly due to perturbation of P53-mediated transcriptional regulation. |