Detail information of PPI "MPI24513"

IdentifierMPI24513
InteractionP53  <==>  TGF-beta
Role & State        ---
Interaction TypeIT:0000068,transcription; IT:0000114,activation; IT:0000078,regulation;
Biological Process        ---
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference18813803_12, GLI2 expression is regulated based on the balance of P53, Notch, and TGF-beta signaling, and Hedgehog signaling activation results in cell survival and proliferation due to transcriptional activation of Hedgehog-target genes, and also partly due to perturbation of P53-mediated transcriptional regulation.