| Identifier | MPI34783 |
| Interaction | alpha4 <==> p53 |
| Role & State | RS:0000077,regulator; |
| Interaction Type | IT:0000128,phosphorylation; IT:0000174,repress; IT:0000068,transcription; IT:0000139,dephosphorylation; |
| Biological Process | BP:0006915,apoptosis; |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 15499020_2, Here we show that alpha4, a noncatalytic subunit of protein phosphatase 2A (PP2A), is required to repress apoptosis in murine cells. alpha4 is a nonredundant regulator of the dephosphorylation of the transcription factors c-Jun and p53. |