Detail information of PPI "MPI38015"

IdentifierMPI38015
Interactioncyclin G1  <==>  p53
Role & StateRS:0000080,suppressor;
Interaction TypeIT:0000128,phosphorylation; IT:0000139,dephosphorylation; IT:0000077,regulate;
Biological Process        ---
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference12668979_2, Recent data show that cyclin G1 can regulate the levels of p53 by a mechanism that involves dephosphorylation of Mdm2 by protein phosphatase 2A.
Reference12668979_9, In conclusion, our data suggest that the decreased tumor susceptibility after loss of cyclin G1 function is caused by the increased tumor suppressor action of p53.