Identifier | MPI38015 |
Interaction | cyclin G1 <==> p53 |
Role & State | RS:0000080,suppressor; |
Interaction Type | IT:0000128,phosphorylation; IT:0000139,dephosphorylation; IT:0000077,regulate; |
Biological Process | --- |
Biological Function | --- |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 12668979_2, Recent data show that cyclin G1 can regulate the levels of p53 by a mechanism that involves dephosphorylation of Mdm2 by protein phosphatase 2A.
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Reference | 12668979_9, In conclusion, our data suggest that the decreased tumor susceptibility after loss of cyclin G1 function is caused by the increased tumor suppressor action of p53.
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