Detail information of PPI "MPI47651"

Interactionp53  <==>  Rb2 proteins
Role & State        ---
Interaction TypeIT:0000128,phosphorylation; IT:0000053,control;
Biological Process        ---
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference9136893_9, We conclude that: (1) Caco-2 cells exert a dominant control against the oncogenic functions of the LT antigen; (2) loss of p53 function is not restrictive for the establishment of polarity and differentiation of the enterocyte lineage; (3) the levels and phosphorylation status of the Rb1 and Rb2 proteins may play important roles in the proliferation and differentiation of normal and neoplastic human colonic mucosa.