Detail information of PPI "MPI47675"

Interactionp53  <==>  cyclins
Role & StateRS:0000074,inhibitor;
Interaction TypeIT:0000108,reduction;
Biological Process        ---
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference12503075_2, The most striking difference found was a significant reduction of the cyclin-dependent kinase inhibitor p27(kip1) in the livers of 3-mo-old p53-/- mice, whereas only small changes were found in the expression of cyclins, cyclin-dependent kinases, and the inhibitors p21(cip1) and p16(ink4a).