Identifier | HPI007946 |
Interaction | Aurora-A <==> p53 |
Role & State | --- |
Interaction Type | IT:0000271,express; |
Biological Process | BP:0008219,cell death; BP:0031099,regeneration; BP:0070265,necrosis; |
Biological Function | --- |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 19435814_0, Aurora-A overexpression in mouse liver causes p53-dependent premitotic arrest during liver regeneration.
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Reference | 19435814_7, Indeed, the premitotic arrest and abnormal cell death, mainly necrosis, caused by Aurora-A overexpression were genetically rescued by p53 knockout.
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