| Identifier | HPI019537 |
| Interaction | Cyclin D1 <==> p53 |
| Role & State | --- |
| Interaction Type | IT:0000099,formation; IT:0000271,express; |
| Biological Process | BP:0040007,growth; |
| Biological Function | --- |
| Subcelluar Location | SCL:0042603,capsule; |
| Detection Method | --- |
| Reference | 11511787_5, Cyclin D1 overexpression showed positive relationships with advanced tumor stage, poor differentiation, larger tumor size, microvascular invasion, intrahepatic meta-stasis, no tumor capsule formation, infiltrative growth, aberrant p53 expression, and high PCNA labeling index (LI) of HCC (p0.05). |
| Reference | 11511787_9, Cyclin D1 overexpression and aberrant p53 expression could be associated with the progression of HBV-related HCC, and might have a less crucial role in the DN-HCC sequence. |