Identifier | HPI033373 |
Interaction | HIF-1 <==> p53 |
Role & State | --- |
Interaction Type | IT:0000071,induction; IT:0000068,transcription; |
Biological Process | BP:0040007,growth; |
Biological Function | --- |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 15592500_4, Further, we provide genetic evidence that induction of Ero1-L alpha by hypoxia and hypoglycemia is mediated by the transcription factor hypoxia-inducible factor 1 (HIF-1) but is independent of p53.
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Reference | 19696166_7, On the contrary, nutlin-3 blunted the hypoxic induction of vascular endothelial growth factor by inactivating HIF-1 even in p53-null cells.
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