| Identifier | HPI053201 |
| Interaction | NF-kappa B <==> p53 |
| Role & State | --- |
| Interaction Type | IT:0000168,inhibit; IT:0000114,activation; |
| Biological Process | BP:0006915,apoptosis; |
| Biological Function | --- |
| Subcelluar Location | SCL:0000008,nucleus; |
| Detection Method | --- |
| Reference | 12398897_0, A novel protein overexpressed in hepatoma accelerates export of NF-kappa B from the nucleus and inhibits p53-dependent apoptosis.
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| Reference | 15230856_8, Hence, the FN gene may be a natural target for HBxAg trans-activation, perhaps through activation of NF-kappa B and inactivation of p53, thereby contributing to the accumulation of FN in the liver over the course of chronic HBV infection.
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