| Identifier | HPI057552 |
| Interaction | PARP <==> p53 |
| Role & State | RS:0000074,inhibitor; |
| Interaction Type | IT:0000128,phosphorylation; |
| Biological Process | BP:0006915,apoptosis; |
| Biological Function | --- |
| Subcelluar Location | SCL:0000006,cytoplasm; |
| Detection Method | --- |
| Reference | 21468663_9, Moreover, the pretreatment with trichostatin A (TSA, a histone deacetylase inhibitor) or TSA in combination with etoposide significantly sensitized HCC cells to apoptosis by inhibiting ERK phosphorylation, reactivating caspases and PARP, and inducing translocation of p53 and Bid to cytoplasm. |