Detail information of PPI "HPI062477"

IdentifierHPI062477
InteractionPlk1  <==>  p53
Role & State        ---
Interaction Type        ---
Biological ProcessBP:0008219,cell death; BP:0006915,apoptotic cell death;
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference19668228_5, Furthermore, Plk1 knockdown in p53-mutated liver tumor cells transactivated p53 family downstream effectors, PUMA, p21(Cip1/WAF1) and 14-3-3sigma, and induced apoptotic cell death.