Identifier | HPI087941 |
Interaction | cyclin D1 and estrogen receptor (ER) alpha <==> p53 |
Role & State | RS:0000067,receptor; |
Interaction Type | IT:0000032,increase; |
Biological Process | --- |
Biological Function | --- |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 19168586_3, LXR suppressed messenger RNA and/or protein expression of Skp2, cyclin A2, cyclin D1 and estrogen receptor (ER) alpha, whereas it increased the expression of p53 at the protein level and maintained the retinoblastoma protein in a hypophosphorylated active form. |