Identifier | HPI088031 |
Interaction | cyclin-dependent kinase <==> p53 |
Role & State | RS:0000074,inhibitor; |
Interaction Type | IT:0000114,activation; IT:0000157,depend; IT:0000077,regulate; IT:0000271,express; |
Biological Process | --- |
Biological Function | BF:0003677,DNA binding; |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 9049201_1, p21(WAF1/CIP1) is a universal cyclin-dependent kinase (cdk) inhibitor, the expression of which is regulated by p53-dependent and p53-independent pathways.
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Reference | 9118908_0, Carcinogenic potential of benzene and toluene when evaluated using cyclin-dependent kinase activation and p53-DNA binding.
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Reference | 9699537_1, The cyclin-dependent kinase inhibitor p21/WAF1 is regulated by p5S3-dependent and p53-independent pathways.
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