Identifier | HPI093175 |
Interaction | heat-shock protein 90 <==> p53 |
Role & State | --- |
Interaction Type | IT:0000059,binding; IT:0000099,formation; IT:0000123,ubiquitination; |
Biological Process | --- |
Biological Function | --- |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 17363365_8, These results support a model in which MDM2 binding induces a conformational change that is opposed by heat-shock protein 90 and precedes p53 ubiquitination. |