Detail information of PPI "HPI102898"

IdentifierHPI102898
Interactionp21/WAF1/Cip1  <==>  p53
Role & StateRS:0000074,inhibitor; RS:0000077,regulator;
Interaction TypeIT:0000271,express; IT:0000078,regulation; IT:0000085,synthesis;
Biological ProcessBP:0001889,liver development; BP:0007049,cell cycle; BP:0032502,development;
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference9618481_1, The cell cycle inhibitor p21/WAF1/Cip1 is expressed in many cell types and is regulated by p53-dependent and p53-independent mechanisms. p21 is an important regulator of hepatocyte cell cycle, differentiation, and liver development, but little is known about the regulation of its synthesis in hepatocytes.