| Identifier | HPI103440 |
| Interaction | p53 <==> ETS |
| Role & State | RS:0000002,activity; |
| Interaction Type | IT:0000068,transcription; IT:0000059,binding; |
| Biological Process | --- |
| Biological Function | BF:0010843,promoter activity; |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 16953216_5, By assessing the promoter activity of a set of linker-scanning mutants of the minimal promoter (-60 to +148 region) in a transient transfection assay, we found that the +1 to + 40 region is critical to HCCS1 gene transcription, containing binding sites for transcription factors NF-kappaB (-21 to +7 and +40 to +26), p53 (+29 to +9) and ETS (+4 to +20 and +23 to +39). |