Identifier | HPI103462 |
Interaction | p53 <==> HBx proteins |
Role & State | --- |
Interaction Type | IT:0000068,transcription; IT:0000371,interaction; |
Biological Process | BP:0040007,growth; BP:0016049,cell growth; |
Biological Function | --- |
Subcelluar Location | --- |
Detection Method | DM:0000019,co-immunoprecipitation; DM:0000019,immunoprecipitation; |
Reference | 21438026_3, This was experimentally addressed through co-immunoprecipitation assays examining the interaction between WtHBx and MutHBx proteins with p53, reporter assays determining the impact of the HBx proteins on p53-mediated gene transcription, and clonogenic survival assays evaluating the effect of HBx on cell growth in lines of varying p53-expression status.
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