| Identifier | HPI103523 |
| Interaction | p53 <==> Nm23 -H1 |
| Role & State | --- |
| Interaction Type | IT:0000320,downregulate; |
| Biological Process | --- |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 12669312_7, This capacity of wt p53 to regulate expression of Nm23-H1 was not only dependent on the endogenous but also the exogenous origin of p53, and could not be reproduced with mutant p53. |
| Reference | 12669312_9, In contrast, increased levels of p53 downregulated the expression of Nm23-H1 at the protein and mRNA levels in RKO and H1299 cells and, as a consequence, increased the invasive ability of both cell types. |