| Identifier | HPI103554 |
| Interaction | p53 <==> TFIIH |
| Role & State | --- |
| Interaction Type | IT:0000114,activation; IT:0000068,transcription; IT:0000059,binding; IT:0000227,bind; |
| Biological Process | BP:0006915,apoptosis; |
| Biological Function | BF:0002039,p53 binding; |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 10074921_3, Our previous work has shown that HBx protein inhibits p53 sequence-specific transcriptional activation, p53-mediated apoptosis and p53 binding to the TFIIH transcription-nucleotide excision repair (NER) factors, including XPB and XPD.
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| Reference | 8521383_8, Binding of p53 to these constituents of the core TFIIH is a process that may be involved in apoptosis.
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