| Identifier | HPI103556 |
| Interaction | p53 <==> TGFbeta |
| Role & State | --- |
| Interaction Type | IT:0000168,inhibit; IT:0000079,suppression; IT:0000076,inhibition; |
| Biological Process | BP:0040007,growth; BP:0006915,apoptosis; BP:0007049,cell cycle; |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 9049198_2, In addition to normal cell cycle progression, p21 is involved in growth suppression mediated by p53 and transforming growth factor beta (TGFbeta), differentiation, and apoptosis.
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| Reference | 9212083_3, However, in primary culture the absence of p53 resulted in increased hepatocyte proliferation indices and decreased sensitivity to proliferation inhibition by TGFbeta.
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