| Identifier | HPI103570 |
| Interaction | p53 <==> VRK2B |
| Role & State | --- |
| Interaction Type | IT:0000364,acetylation; IT:0000068,transcription; IT:0000123,ubiquitination; IT:0000353,phosphorylate; IT:0000114,activation; |
| Biological Process | --- |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 16704422_10, Indeed, the p53 phosphorylated by VRK2B shows a reduction in ubiquitination by Mdm2 and an increase in acetylation by p300.
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| Reference | 16704422_11, Endogenous p53 is also phosphorylated in Thr18 by VRK2B, promoting its stabilization and transcriptional activation in A549 cells.
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