Identifier | HPI103593 |
Interaction | p53 <==> become growth factor- |
Role & State | --- |
Interaction Type | IT:0000099,formation; IT:0000057,anchor; |
Biological Process | BP:0040007,growth; |
Biological Function | --- |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 19472310_5, After 40 cell generations the pX-expressing polyploid cultures exhibit loss of p53 function and become growth factor- and anchorage-independent, indicative of oncogenic transformation. |