| Identifier | HPI103595 |
| Interaction | p53 <==> beta-catenin |
| Role & State | --- |
| Interaction Type | IT:0000078,regulation; IT:0000114,activation; |
| Biological Process | --- |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 12439747_11, These data suggest that inactivation of p53 is an important cause of aberrant accumulation of beta-catenin in cancer cells.
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| Reference | 15362367_4, Of the cases, 30 (55%) were positive for 1 or more proteins: AFP, 19 cases (35%); p53, 12 cases (22%); and beta-catenin, 9 cases (16%).
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| Reference | 9537436_5, We found that the down-regulation of E-cad, alpha-catenin, and beta-catenin expression significantly correlated with tumor high grade, but not with vascular invasion, metastasis, p53 expression, Ki-67 labeling, or c-erbB2 expression, except for beta-catenin, the down-regulation of which was associated with c-erbB2 down-regulation.
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