Identifier | HPI103607 |
Interaction | p53 <==> cyclin-dependent kinase |
Role & State | RS:0000074,inhibitor; RS:0000080,suppressor; |
Interaction Type | IT:0000371,interaction; IT:0000080,effect; |
Biological Process | --- |
Biological Function | --- |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 12665691_3, Peptide sequencing revealed three proteins whose interaction with p53 had not been previously reported: a cyclin-dependent kinase inhibitor p57/Kip2, a serine/threonine protein phosphatase PP1C, and hemoglobin.
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Reference | 9022146_1, CIP1/WAF1, a critical downstream effector of tumor suppressor p53, encodes a cyclin-dependent kinase inhibitor.
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