| Identifier | HPI103609 |
| Interaction | p53 <==> dominant-negative p53 |
| Role & State | --- |
| Interaction Type | IT:0000271,express; |
| Biological Process | BP:0010467,gene expression; |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 8665514_7, To examine possible mechanisms by which p53 may regulate IR gene expression, we show that p53 can repress the IR promoter and that a dominant-negative p53 (248Q) can de-repress the promoter in cells containing normal p53. |