| Identifier | HPI103630 |
| Interaction | p53 <==> histone deacetylase |
| Role & State | RS:0000002,activity; RS:0000080,suppressor; RS:0000078,repressor; |
| Interaction Type | IT:0000026,interact; IT:0000068,transcription; IT:0000227,bind; |
| Biological Process | --- |
| Biological Function | BF:0004407,histone deacetylase activity; BF:0019213,deacetylase activity; |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 11818510_0, Repression of hepatocyte nuclear factor 4alpha tumor suppressor p53: involvement of the ligand-binding domain and histone deacetylase activity.
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| Reference | 11818510_8, These results suggest that p53, like other transcriptional repressors, inhibits transcription by multiple mechanisms, one of which involves interaction with the ligand-binding domain and recruitment of histone deacetylase activity.
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