Detail information of PPI "HPI103635"

IdentifierHPI103635
Interactionp53  <==>  insulin-like growth factor-binding protein-1
Role & State        ---
Interaction TypeIT:0000275,mediate; IT:0000099,formation;
Biological ProcessBP:0008219,cell death; BP:0040007,growth;
Biological Function        ---
Subcelluar Location        ---
Detection Method        ---
Reference18285608_4, It appears that p53-mediated induction of the gene that encodes insulin-like growth factor-binding protein-1 (IGFBP1) attenuates the cell death response in hepatocytes by preventing the formation of a complex between p53 and the proapoptotic protein BAK.