Identifier | HPI103719 |
Interaction | p53 <==> p27 |
Role & State | --- |
Interaction Type | IT:0000025,associate; IT:0000114,activation; IT:0000128,phosphorylation; IT:0000139,dephosphorylation; |
Biological Process | --- |
Biological Function | --- |
Subcelluar Location | SCL:0000010,cytosol; |
Detection Method | --- |
Reference | 15004518_9, In conclusion, the results demonstrated that TGF-beta1-induced p53 dephosphorylation is associated with caspase-3 activation, and cytosolic translocation of p21(Cip1/Waf1) and p27(Kip1), resulting in decreased expression of Cdks and cyclins. |