Identifier | HPI103744 |
Interaction | p53 <==> p53+/- ; p53 -/-) |
Role & State | --- |
Interaction Type | --- |
Biological Process | BP:0000279,M-phase; |
Biological Function | --- |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 9425920_3, The hepatocytes of heterozygous or homozygous p53-knockout mice (p53+/-; p53-/-), as well as knockout mice expressing one allele of p53ser246 (p53+/-, p53*; p53-/-, p53*), do not undergo normal polyploidization with aging and show an increase in the number of cycling (G1-, S-, and M-phase) cells. |