| Identifier | HPI103833 |
| Interaction | p53 <==> topoisomerase I inhibitor |
| Role & State | RS:0000074,inhibitor; |
| Interaction Type | --- |
| Biological Process | --- |
| Biological Function | --- |
| Subcelluar Location | --- |
| Detection Method | --- |
| Reference | 15604280_2, Using isogenic human colon cancer cells that differ only in their p53 status, we demonstrate that loss of p53 renders tumor cells relatively resistant to the topoisomerase I inhibitor, irinotecan. |