Identifier | MPI07468 |
Interaction | Cdk2 ( - / - ) mouse embryonic fibroblasts <==> p53 |
Role & State | --- |
Interaction Type | IT:0000114,activation; IT:0000357,response; |
Biological Process | --- |
Biological Function | --- |
Subcelluar Location | --- |
Detection Method | --- |
Reference | 17942597_4, Cdk2(-/-) mouse embryonic fibroblasts in vitro as well as regenerating liver cells after partial hepatectomy (PH) in Cdk2(-/-) mice, arrest promptly at the G1/S checkpoint in response to gamma-irradiation due to activation of p53 and p21 inhibiting Cdk1.
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